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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOP2 All Species: 28.18
Human Site: Y401 Identified Species: 47.69
UniProt: P46087 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P46087 NP_001028886.1 812 89302 Y401 A P G G K T S Y M A Q L M K N
Chimpanzee Pan troglodytes XP_001162276 812 89269 Y401 A P G G K T S Y M A Q L M K N
Rhesus Macaque Macaca mulatta XP_001105884 811 89266 Y400 A P G G K T S Y M A Q L M K N
Dog Lupus familis XP_854432 985 108067 Y572 A P G G K T S Y I A Q L M K N
Cat Felis silvestris
Mouse Mus musculus Q922K7 793 86733 Y386 A P G G K T S Y I A Q L M K N
Rat Rattus norvegicus XP_235295 772 84951 Y381 A P G G K T S Y I A Q L M K N
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_416502 682 76182 E306 I N F L E A N E V P R P V T I
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001922354 739 83513 N332 A L I N R G V N L D P L G K W
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_610786 891 99823 H452 A P G G K G S H I A S I M K N
Honey Bee Apis mellifera XP_001121968 582 67009 S206 Q C V F T F P S E E E L A D I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_787141 1076 119756 Y678 S P G S K T T Y I A A L M K N
Poplar Tree Populus trichocarpa XP_002300386 476 53332 P100 L I E A F E K P R P T C L R T
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_194390 671 75524 P295 N R G V N L D P L S K W S K V
Baker's Yeast Sacchar. cerevisiae P40991 618 69794 Y241 D I C E Y F G Y T P F L A E K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.1 95.1 68.8 N.A. 75.8 75.1 N.A. N.A. 55.5 N.A. 53 N.A. 41 37.5 N.A. 37.4
Protein Similarity: 100 99.3 96.1 73.8 N.A. 83.2 82 N.A. N.A. 65.3 N.A. 66.5 N.A. 57.6 49.2 N.A. 49.7
P-Site Identity: 100 100 100 93.3 N.A. 93.3 93.3 N.A. N.A. 0 N.A. 20 N.A. 66.6 6.6 N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. N.A. 33.3 N.A. 33.3 N.A. 86.6 13.3 N.A. 86.6
Percent
Protein Identity: 37.9 N.A. N.A. 39.7 37.4 N.A.
Protein Similarity: 47.6 N.A. N.A. 55.6 52 N.A.
P-Site Identity: 0 N.A. N.A. 13.3 13.3 N.A.
P-Site Similarity: 13.3 N.A. N.A. 33.3 20 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 58 0 0 8 0 8 0 0 0 58 8 0 15 0 0 % A
% Cys: 0 8 8 0 0 0 0 0 0 0 0 8 0 0 0 % C
% Asp: 8 0 0 0 0 0 8 0 0 8 0 0 0 8 0 % D
% Glu: 0 0 8 8 8 8 0 8 8 8 8 0 0 8 0 % E
% Phe: 0 0 8 8 8 15 0 0 0 0 8 0 0 0 0 % F
% Gly: 0 0 65 50 0 15 8 0 0 0 0 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 0 % H
% Ile: 8 15 8 0 0 0 0 0 36 0 0 8 0 0 15 % I
% Lys: 0 0 0 0 58 0 8 0 0 0 8 0 0 72 8 % K
% Leu: 8 8 0 8 0 8 0 0 15 0 0 72 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 22 0 0 0 58 0 0 % M
% Asn: 8 8 0 8 8 0 8 8 0 0 0 0 0 0 58 % N
% Pro: 0 58 0 0 0 0 8 15 0 22 8 8 0 0 0 % P
% Gln: 8 0 0 0 0 0 0 0 0 0 43 0 0 0 0 % Q
% Arg: 0 8 0 0 8 0 0 0 8 0 8 0 0 8 0 % R
% Ser: 8 0 0 8 0 0 50 8 0 8 8 0 8 0 0 % S
% Thr: 0 0 0 0 8 50 8 0 8 0 8 0 0 8 8 % T
% Val: 0 0 8 8 0 0 8 0 8 0 0 0 8 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % W
% Tyr: 0 0 0 0 8 0 0 58 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _